In a press briefing on Saturday, Sima-Sadat Lari said the virus has killed 126 patients since Friday noon, increasing the overall death toll to 20,502.
So far, she added, 307,702 patients have recovered from the disease or been discharged from the hospital.
Lari said 3,850 patients are also in critical conditions caused by more severe infection.
The spokeswoman noted that 3,011,310 COVID-19 tests have been taken across the country so far.
She said the high-risk “red” zones include Tehran, Qom, Mazandaran, East Azarbaijan, Isfahan, Ardabil, Yazd, Markazi, Khorasan Razavi, North Khorasan, Semnan, Gilan, Golestan, and Kerman provinces.
The “orange” zones also include Lorestan, Alborz, Hormozgan, Ilam, Fars, Hamadan, Bushehr, West Azarbaijan, Qazvin, Chaharmahal and Bakhtiari, Kohgiluyeh and Boyer-Ahmad, and Zanjan provinces, she added.