The OIC convened in Jeddah on Monday to discuss the plan Trump unveiled alongside Israeli prime minister Benjamin Netanyahu at the White House on Tuesday.
The 57-member organization said it “calls on all member states not to engage with this plan or to cooperate with the US administration in implementing it in any form”.
The deal would, among other contentious things, enshrine Jerusalem al-Quds as “Israel’s undivided capital” and allow the regime to annex settlements in the occupied West Bank and the Jordan Valley.
All Palestinian groups have angrily rejected the plan, while Israeli groups of different political persuasions have enthusiastically embraced it, hailing it for offering them more than they expected.
Palestinian Authority leader Mahmoud Abbas on Saturday cut relations with the US and Israel after saying he did not want his name to go down in history for betraying the Palestinians.