Behzad Amiri told Iranian media on Thursday that the best way to contain the spread of the disease was for individuals to adhere to hygiene standards.
Monkeypox is a rare disease caused by a virus with the same name, which is part of the same family as smallpox, although typically less severe.
It causes flu-like symptoms such as fever and chills, and a rash, in later stages, which can take weeks to disappear.
The disease used to be endemic to Africa but a recent outbreak across the US, Europe, Australia and the Middle East has surprised health experts, prompting fears of a wider outbreak.
The disease is mild and usually non-fatal. The World Health Organization (WHO) has said the monkeypox outbreak, while “not normal,” is still “containable.”